Patent
Lactiplantibacillus plantarum TENSIA®
Invention: 'An isolated strain of the microorganism Lactobacillus plantarum Tensia DSM 21380 as an antimicrobial and antihypertensive probiotic, a food product and composition containing it, and the use of the microorganism for the preparation of an antihypertensive drug and a method for suppressing the action of non-sterile lactobacilli in food'.
Authors Epp Songisepp, Marika Mikelsaar, Merle Rätsep, Mihkel Zilmer, Pirje Hütt, Meeme Utt, Kersti Zilmer, Janne Üksti, Siiri Kõljalg.
The patent has been transferred to the subsidiary Nordwise Biotech OÜ.
Patents:
Estonian patent EE05340, Patent-issued 16.08.2010,
“Isoleeritud mikroorganismi tüvi Lactobacillus plantarum Tensia DSM 21380 kui antimikroobne ning vererõhku alandav probiootik, seda sisaldav toiduaine ja kompositsioon ning mikroorganismi kasutamine vererõhku langetava ravimi valmistamiseks ning meetod toiduaines mittestarter-laktobatsillide toime allasurumiseks”.
Russian patent RU2477750, Patent-issued 20.03.2013, “Изолированный штамм микроорганизма Lactobacillus plantarum Tensia DSM 21380 как противомикробный и гипотензивный пробиотик, продукт питания и композиция, содержащая упомянутый микроорганизм, и применение упомянутого микроорганизма для получения гипотензивного лекарственного средства, способ подавления патогенов и побочных лактобактерий в продукте питания“.
European patentEP2309870, patent-issued 04.05.2012, “Isolated microorganism strain Lactobacillus plantarum Tensia DSM 21380 as antimicrobial and antihypertensive probiotic, food product and composition comprising said microorganism and use of said microorganism for preparation of antihypertensive medicine and method for suppressing pathogens and non-starter lactobacilli in food product”.
EP2309870 has been enforced in the following countries:
United Kingdom GB/EP2309870
Germany DE/EP2309870
France FR/EP2309870
Finland FI/EP2309870
Poland PL/EP2309870
Lithuania LT/EP2309870
Latvia LV/EP2309870
Sweden SE/EP2309870
Czech Republic CZ/EP2309870
Hungary HU/EP2309870
Korean patent KR10-1587195, Patent-issued 14.01.2016, 항균 및 항고혈압 프로바이오틱인 단리된 미생물 균주 락토바실러스 플란타룸 텐시아 ＤＳＭ 21380과, 이 미생물을 포함하는 식품과 조성물 및 항고혈압제의 제조를 위한 이 미생물의 용도와, 식품에서 병원체 및 논-스타터 락토바실러스를 억제하기 위한 방법
Invention: 'An isolated strain of the microorganism Lactobacillus plantarum Tensia DSM 21380 as an antimicrobial and antihypertensive probiotic, a food product and composition containing it, and the use of the microorganism for the preparation of an antihypertensive drug and a method for suppressing the action of non-sterile lactobacilli in food'.
Patents:
Estonian patent EE05340, Patent-issued 16.08.2010,
“Isoleeritud mikroorganismi tüvi Lactobacillus plantarum Tensia DSM 21380 kui antimikroobne ning vererõhku alandav probiootik, seda sisaldav toiduaine ja kompositsioon ning mikroorganismi kasutamine vererõhku langetava ravimi valmistamiseks ning meetod toiduaines mittestarter-laktobatsillide toime allasurumiseks”.
Russian patent RU2477750, Patent-issued 20.03.2013, “Изолированный штамм микроорганизма Lactobacillus plantarum Tensia DSM 21380 как противомикробный и гипотензивный пробиотик, продукт питания и композиция, содержащая упомянутый микроорганизм, и применение упомянутого микроорганизма для получения гипотензивного лекарственного средства, способ подавления патогенов и побочных лактобактерий в продукте питания“.
European patent EP2309870, Patent-issued 04.05.2012, “Isolated microorganism strain Lactobacillus plantarum Tensia DSM 21380 as antimicrobial and antihypertensive probiotic, food product and composition comprising said microorganism and use of said microorganism for preparation of antihypertensive medicine and method for suppressing pathogens and non-starter lactobacilli in food product”.
EP2309870 has been enforced in the following countries:
United Kingdom GP/EP2309870
Sweden SE/EP2309870
Germany DE/EP2309870 (60 2009 007 496.2)
France FR/EP2309870
Finland FI/EP2309870Czech CZ/EP2309870
Poland PL/EP2309870
Hungary HU/EP2309870
Lithuania LT/EP2309870
Latvia LV/EP2309870
Korean patent KR10-1587195, Patent-issued 14.01.2016, 항균 및 항고혈압 프로바이오틱인 단리된 미생물 균주 락토바실러스 플란타룸 텐시아 ＤＳＭ 21380과, 이 미생물을 포함하는 식품과 조성물 및 항고혈압제의 제조를 위한 이 미생물의 용도와, 식품에서 병원체 및 논-스타터 락토바실러스를 억제하기 위한 방법
Lactiplantibacillus plantarum INDUCIA®
Invention:An isolated strain of the microorganism Lactobacillus plantarum Inducia DSM 21379 as a probiotic that enhances the body's natural defences, a food product and composition containing it, and the use of the microorganism for the production of a cellular immunity-enhancing drug.
Authors Marika Mikelsaar, Epp Songisepp, Imbi Smidt, Jelena Stsepetova, Pirje Hütt, Mihkel Zilmer, Kai Truusalu, Kalle Kilk.
The patent has been transferred to the subsidiary Nordwise Biotech OÜ.
Patents:
Estonian patent EE05341, Patent-issued 16.08.2010, “Isoleeritud mikroorganismi tüvi Lactobacillus plantarum Inducia DSM 21379 kui organismi loomulikku kaitsevõimet tõstev probiootik, seda sisaldav toiduaine ja kompositsioon ning mikroorganismi kasutamine rakulist immuunsust tõstva ravimi valmistamiseks”.
Russian patent RU2486234, Patent-issued 27.06.2013 “Изолированный штамм микроорганизма Lactobacillus Plantarum Inducia DSM 21379 в качестве пробиотика, усиливающего врожденный иммунитет организма, продукт и композиция, содержащие упомянутый микроорганизм, и применение упомянутого микроорганизма для изготовления лекарственного средства, которое усиливает клеточный иммунитет”.
European patent EP2288360, Patent-issued 14.12.2011,“Isolated Lactobacillus plantarum strain Inducia DSM 21379 as probiotic that enhances natural immunity and food products and medicinal preparations comprising it”.
EP2288360 is enforced and valid in the following countries:
United Kingdom GB/EP2288360
Sweden SE/EP2288360
Germany DE/EP2288360 (60 2009 004 223.8)
France FR/EP2288360
Finland FI/EP2288360
Denmark DK/EP2288360
Poland PL/EP2288360
Lithuania LT/EP2288360
Latvia LV/EP2288360
Korean patent KR10-1595042, Patent-issued 11.02.2018 “자연 면역을 증가시키는 프로바이오틱인 단리된 락토바실러스 플란타룸 균주 인듀시아 ＤＳＭ 21379와, 이를 포함하는 식품과 의약적 제제 (Isolated Lactobacillus plantarum strain Inducia DSM 21379 as probiotic that enhances natural immunity and food products and medicinal preparations comprising it).
Invention:Invention:Composition containing the hypocholestemic probiotic microorganism strain Lactobacillus plantarum Inducia DSM 21379 for use in the prevention of cardiovascular disease.
Authors Marika Mikelsaar, Epp Songisepp, Pirje Hütt, Imbi Smidt, Kai Truusalu, Merle Rätsep, Siiri Kõljalg, Jelena Stsepetova, Kalle Kilk, Mihkel Zilmer, Epp Sepp, Raik-Hiio Mikelsaar.
The patent has been transferred to the subsidiary Nordwise Biotech OÜ.-le.
Patents:
Estonian patent EE05799, Patent-issued 16.10.2017, “Hüpokolestereemilist probiootilist mikroorganismi tüve Lactobacillus plantarum Inducia DSM 21379 sisaldav kompositsioon kasutamiseks südame-veresoonkonnahaiguste ennetamiseks”.
USA patent US10272122, Patent-issued 30.04.2019, “Lactobacillus plantarum Inducia DSM 21379 as enhancer of cellular immunity, hypocholesterolemic and anti-oxidative agent and antimicrobial agent against Clostridium difficile”.
European patent EP3193895, Patent-issued 15.04.2020, “Lactobacillus plantarum Inducia DSM 21379 as hypocholesterolemic agent and antimicrobial agent against Clostridium Difficile”.
Invention: a composition containing Lactobacillus plantarum INDUCIA® DSM 21379 for use in reducing the risk of Clostridium difficile-induced diarrhoea (CDAD).
The patent has been transferred to the subsidiary Nordwise Biotech OÜ.
Estonian patent EE05809, Patent-issued 16.10.2017, “Probiootilist mikroorganismi tüve Lactobacillus plantarum Inducia DSM 21379 sisaldav kompositsioon kasutamiseks Clostridium difficile põhjustatud kõhulahtisuse (CDAD) riski vähendamiseks”.
Lactiplantibacillus plantarum MCC1 and MCC2
Invention:Isolated micro-organism strains L. plantarum MCC1 DSM 23881 and Lactobacillus gasser MCC2 23882 and their use.
Authors Tiiu Kullisaar, Mihkel Zilmer, Ene Tammsaar, Andre Veskioja, Kersti Zilmer, Lauri Bobrovski, Kersti Ehrlich, Merle Rätsep, Margus Punab, Maire Vasar, Marika Mikelsaar.
The patent has been transferred to the subsidiary Nordwise Biotech OÜ.
Patents:
Estonian patent EE05721, Patent-issued 15.08.2014,”Isoleeritud mikroorganismi tüvi L. plantarum MCC1 DSM 23881 ja selle kasutamine“.
Estonian patent EE05750, Patent-issued 15.06.2015, „Isoleeritud mikroorganismi tüvi Lactobacillus gasseri MCC2 DSM 23882 ning selle kasutamine”.
European patent EP2678419, Patent-issued23.09.2015 “Isolated microorganism strain Lactobacillus plantarum MCC1 DSM 23881 and its use“.
EP2678419 is enforced and valid in the following countries:
Ireland IE/EP2678419
Ireland Ireland IE/EEA IE/EE2678419
Latvia LV/EP2678419
France FR/EP2678419
Germany DE/EP2678419
Serbia RS/EP2678419
Finland FI/EP2678419
United Kingdom UK/EP2678419
Japanese patent JP5785275, Patent-issued 31.07.2015, „Isolated microorgasnism strains Lactobacillus plantarum MCC1 DSM 23881 and Lactobacillus gasseri MCC2 DSM 23882 and their use“.
Russian patent RU2603059, issued 20.11.2016, “Изолированные штаммы микроорганизмов Lactobacillus plantarum MCC1 DSM 23881 и Lactobacillus gasseri MCC2 DSM 23882 и их применение” (Isolated microorgasnism strains Lactobacillus plantarum MCC1 DSM 23881 and Lactobacillus gasseri MCC2 DSM 23882 and their use)“.
Korean patent KR10-1586778, Patent-issued 31.07.2015, “분리된 미생물 균주 락토바실러스 플란타룸 MCC1 DSM 23881 및 락토바실러스 가서리” MCC2 DSM 23882와 그의 용도 ”(Isolated microorganism strains Lactobacillus plantarum MCC1 DSM 23881 and Lactobacillus gasseri MCC2 DSM 23882 and their use).
Chinese patent CN103649304, Patent-issued 23.03.2016 „Isolated microorganism strains Lactobacillus plantarum MCC1 DSM 23881 and its use“
Chinese patent CN105733983B Patent-issued 06.09.2019, “Isolated microorganism strain Lactobacillus gasseri MCC2 DSM 23882 and its use”.
Lactiplantibacillus plantarum TAK 59
Invention: Invention: Micro-organism strain Lactobacillus plantarum TAK 59 NCIMB 42150 and its use.
Authors Andres Olt, Helgi Kaldmäe, Olav Kärt, Meelis Ots, Epp Songisepp, Merle Rätsep, Kristiina Kokk, Jelena štšepetova, Siiri Kõljalg.
The patent has been transferred to the subsidiary Nordwise Biotech OÜ..
Patents:
Estonian patent EE05746, Patent-issued15.05.2015, “Mikroorganism Lactobacillus plantarum TAK 59 NCIMB42150 ja selle kasutamine”.
European patent EP3027734, Patent-issued 25.10.2017, “Isolated microorganism strain Lactobacillus plantarum TAK 59 NCIMB42150 and its use”.
EP3027734 on jõustatud ja kehtiv järgmistes riikides:
Leedu LT/EP3027734
Läti LV/EP3027734
Soome FI/EP3027734
Russian patent RU2645471, Patent-issued 21.02.2018 “Isolated microorganism strain Lactobacillus plantarum TAK 59 NCIMB42150 and its use”.
Japanese patent JP6514201B2, Patent-issued 19.04.2019, “Isolated microorganism strain Lactobacillus plantarum TAK 59 NCIMB42150 and its use”.
Lactiplantibacillus brevis TAK 124-1
Invention: Isolated micro-organism strain Lactobacillus brevis TAK 124-1 NCIMB42149 and its use.
The patent has been assigned to the subsidiary Nordwise Biotech OÜ.
Patents:
Estonian patent EE05756, issued 16.11.2015, "Isolated microorganism strain Lactobacillus brevis TAK 124-1 NCIMB42149 and its use".
Eurasian patent EA033289, issued 30.09.2019, 'Microorganism Lactobacillus brevis TAK 124-1 NCIMB42149 and its use'.
Lactobacillus buchneri BioCC 203 and BioCC 228
Micro-organism strain Lactobacillus buchneri BioCC 203 DSM 32650 and its use
Estonian patent EE05825 Patent-issued 17.8.2020
Authors Epp Songisepp, Oksana Gerulis, Liina Kuus, Sirje Kuusik, Merle Muruvee, Anette Sibrits, Meelis Ots, Andres Olt
Micro-organism Lactobacillus buchneri BioCC 228 DSM 32651 and its use
Estonian patent EE05834 Patent-issued 17.05.2021
Authors Epp Songisepp, Oksana Gerulis, Liina Kuus, Sirje Kuusik, Merle Muruvee, Anette Sibrits, Meelis Ots, Andres Olt.
Microorganism strains Lactobacillus buchneri BioCC 203 DSM 32650 and Lactobacillus buchneri BioCC 228 DSM 32651 and their use
Japanese patent JP7250783 Patent issued 03.04.2023
Eurasian patent EA041159 Patent issued 20.09.2022
International patent application PCT/EE2018)000003 (28.09.2018)
Chinese patent application CN201880077117.6 (28.05.2020)
European patent application EP18793358.5 (22.04.2020)
Pediococcus acidilactici TAK 589 Coccobest
Micro-organism strain Pediococcus acidilactici TAK 589 Coccobest as an antimicrobial and antioxidant probiotic.
Authors Pille Palumaa, Tanel Kaart, Kristiina Märs, Meelis Ots, Eve Rihma, Jaan Vihalemm, Epp Songisepp, Liina Kuus, Heili Sadam.
Estonian patent 05844 Patent-issued 15.06.2022
International patent application PCT/IB2021/000739 WO2022058798 (17.09.2021)
European patent application EP21834863.9 (17.09.2021; 30.03.2023)
US patent application US202118026904, US2023330161 (17.09.2021; 17.03.2023)
Chinese patent application CN116583193 (17.09.2021; 18.05.2023)
Japanese patent application JP2023542335 (17.09.2021; 22.05.2023)
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Method for the identification of cows, mothers of dairy bulls and daughters of dairy bulls producing milk with modified curdling characteristics
Authors Elli Pärna, Mirjam Vallas, Kalev Pärna, Tanel Kaart.
Estonian patent EE05659 Patent-issued 17.06.2013.